OUR EXPERTISE
- Chemical and biological stability studies in stability chambers
- In vitro permeability testing of your compound using reconstituted tissue models (skin, intestine, mucosa, others)
- In vitro cytotoxicity assays using various approaches (AlamarBlue, LDH, ATP, membrane integrity measurement)
- Toxicity in rodents following single or repeated administration by various routes (intravenous tail vein, intravenous in canulated rodents, intranasal, subcutaneous, oral, intraperitoneal, intramuscular)
- Observations of clinical signs
- Analysis of hematological and biochemical blood profiles
- Gross necropsy
- Histological analysis
- Biodistribution study using fluorescent compounds
- In vivo and ex vivoimaging (IVIS spectrum imaging system)
- Immunofluorescence on slide and quantitative measurements with CellQuant software (3DHISTECH)
- Pharmacokinetics in rodents following administration by various routes (intravenous, intranasal, subcutaneous, oral, intraperitoneal, intramuscular)
- Small molecule analysis by LC-MS/MS or GC-MS/MS
- Calculation of pharmacokinetic parameters
- Development of tests or models for your specific needs
Passionate about the effects of your assets
Is your asset effective and safe?
PHARMACOLOGY
TransBIOTech performs your in vitro, ex vivo and in vivo assays to evaluate the biological properties of your compounds and formulations.
CONTACT US
Your R&D projects require distinctive expertise that cannot be improvised. TransBIOTech provides you with a complete and proven know-how with 150+ achievements per year, with more than 50 partners.
Pharmacology
Your TEAM
Pharmacology
Yvan Boutin
Research Professor - Biology
Samuel Des Becquets
Animal Health Technician
Gabrielle St-Pierre
Animal Health Technician
Frédéric Couture
Researcher - pharmacology, Preclinical Research Manager
Sara Carignan
Animal Health Technician
Julia Galimi
Animal Health Technician
Marie-Eve Janelle
Research Professor - Biology
Carole-Ann Huppé
Researcher - pharmacology
Isabelle Bolduc
Animal Health Technician